Patient information, made human

Make every patient’s first impression a clear one.

Clinical trials, clearly explained.

Trial Guide turns approved clinical trial materials — PISs, visit guides, study information — into short, plain-English videos people can understand with confidence.

Trial Guide logo — navy head outline with a violet and pink play-button speech bubble, with the words Clinical trials, clearly explained.

The problem

Consent starts with understanding.

Patient Information Sheets have to do a difficult job. They carry important detail, but they are often long, dense and written well above the reading level many patients need.

When the information is hard to follow, the decision is harder too. Clearer communication helps patients understand what they are being asked to consider — and supports better-quality informed consent.

Trial Guide secondary logo lockup

What we make

The approved sheet, made easier to take in.

We create short, sponsor-branded videos from your approved clinical trial materials — starting with the Patient Information Sheet (PIS).

  • Plain EnglishWritten to an age-11 reading level.
  • TraceableEvery line is checked against the approved source.
  • PurposefulTypically 60–90 seconds, focused on what matters.
  • Ready to useMade in your study’s visual identity.

Why it matters

Clearer information is part of better research.

Trial Guide is aligned with the public aims shared across NIHR and NHS research: helping people understand research, supporting informed choices and making it easier for studies to reach the people they need.

We are independent. This is alignment with those aims, not an endorsement, partnership or affiliation.

How it works

From approved page to published video.

Send the approved PIS

Start with the document your study has already approved — a PIS, visit guide, or any patient-facing material. Nothing gets invented: every word we build from traces back to your approved source.

We storyboard the script

Plain English, scene by scene. We shape the narrative, write the voiceover, and design the visuals — then map every line of the script back to the source document.

Sponsor submits script & storyboard to ethics

The script and storyboard travel through your own ethics route, alongside your approved material. You keep the pen at every stage — we support, you decide.

Review and sign off the draft video

You see the full draft in a controlled review. Comment, refine, approve — nothing is published until your team signs it off.

Receive your video

Your finished video arrives subtitled and sponsor-branded — ready for your study site, emails, clinic screens, and social channels.

List your video — TrialConnect or your own site

One clear video, every home: list it on TrialConnect, your own study website, or hand it straight to sites. Wherever your patients look, it works.

Guidance & evidence

Built the way the system asks.

Across the UK health system, the direction is consistent: participant information should be short, plain, and genuinely understandable. The NHS Accessible Information Standard requires information to be provided in formats patients can understand; the Health Research Authority pushes for participant information focused on what people actually need to decide; and NIHR consistently identifies clearer information as a lever for trial recruitment and retention. Trial Guide exists to make that standard easy to hit — video that carries your approved words to every reading age.

About Trial Guide

Built by people who understand clinical research.

Trial Guide is made by clinical research professionals who know the pressure behind each study milestone — and the care patients deserve when they are making a decision.

Our focus is simple: make the approved information clearer, without making it less rigorous.

Start a conversation

Bring your trial to life.

Tell us about your study and we’ll help you find the right place to start.

[email protected]

Or send a brief to your usual Trial Guide contact.